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IndicationsDANTRIUM is indicated in controlling the manifestations of clinical spasticity resulting from serious chronic disorders such as spinal cord injury stroke cerebral palsy or multiple sclerosis. It is of particular benefit to the patient whose functional rehabilitation has been retarded by the sequelae of spasticity. Such patients must have presumably reversible spasticity where relief of spasticity will aid in restoring residual function. There is no evidence that patients with contractures will benefit. DANTRIUM is not indicated in the treatment of skeletal muscle spasm resulting from rheumatic disorders or electroconvulsive therapy.If improvement occurs it will ordinarily occur within the dosage titration schedule (see DOSAGE AND ADMINISTRATION) as manifested by a decrease in the severity of spasticity and the ability to resume a daily function not quite attainable without DANTRIUM.Occasionally subtle but meaningful improvements in spasticity may occur with DANTRIUM therapy. In such instances information regarding improvement should be solicited from the patient and those who are in constant daily contact and attendance with him. Brief withdrawal of DANTRIUM for a period of 2 to 4 days will frequently demonstrate exacerbation of the manifestation of spasticity and may serve to confirm a clinical impression.A decision to continue the administration of DANTRIUM on a long term basis is justified if introduction of the drug into the patient's regimen produces a significant reduction in painful and/or disabling spasticity such as clonus or permits a significant reduction in the intensity and/or degree of nursing care required or rids the patient of an annoying manifestation of spasticity considered important by the patient himself.Dosage and Administration:Prior to the administration of DANTRIUM consideration should be given to the potential response to treatment. A decrease in spasticity sufficient to allow a daily function not otherwise attainable should be the therapeutic goal of treatment with DANTRIUM. Refer to the INDICATIONS section for a description of the response to be anticipated.It is important to establish a therapeutic goal (regain and maintain a specific function such as therapeutic exercise program utilisation of braces transfer manoeuvres etc.) before beginning DANTRIUM therapy. Dosage should be increased until the maximum performance compatible with the dysfunction due to underlying disease is achieved. No further increase in dosage is then indicated.Usual Dosage It is important that the dosage be titrated and individualised for maximum effect. The lowest dose compatible with optimal response is recommended.In view of the potential for liver damage in long-term DANTRIUM use therapy should be stopped if benefits are not evident within 45 days.Adults Begin therapy with 25 mg once daily; increase to 25 mg two three or four times daily and then by increments of 25 mg up to as high as 50 mg two three or four times daily if necessary. The maximum recommended dose is 200 mg/day. As most patients will respond to this or a lower dose and hepatotoxicity appears to be dose-related above 200 mg/day higher doses should be used only rarely and with close monitoring. (See WARNINGS). Doses higher than 400 mg/day should not be used.Each dosage level should be maintained for four to seven days to determine the patient's response. The dose should not be increased beyond and may even have to be reduced to the amount at which the patient received maximal benefit without adverse effects.Children A similar approach should be utilised starting with 0.5 mg/kg of body weight twice daily; this is increased to 0.5 mg/kg three or four times daily and then by increments to a maximum of 2 mg/kg three times a day. Doses higher than 50 mg four times daily should not be used in children.

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Discount Prescription Drugs & Pain Medicine: Anaprox (Naproxen) Anaprox (Naproxen) is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and swelling (inflammation). It is also used to treat headaches muscle aches backaches etc. Buy Anaprox (Naproxen) and other Pain Medicine products online at Medstore. About Anaprox (Naproxen): Product Type: Pain Medicine Brand name: Anaprox Generic name: Naproxen What is anaprox? Naproxen is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Naproxen works by reducing hormones that cause inflammation and pain in the body. Naproxen is used to treat pain or inflammation caused by conditions such as arthritis ankylosing spondylitis tendinitis bursitis gout or menstrual cramps. Naproxen may also be used for purposes other than those listed in this medication guide. What is the most important information I should know about anaprox? This medicine can increase your risk of life-threatening heart or circulation problems including heart attack or stroke. This risk will increase the longer you use anaprox. Do not use this medicine just before or after having heart bypass surgery (also called coronary artery bypass graft or CABG). Seek emergency medical help if you have symptoms of heart or circulation problems such as chest pain weakness shortness of breath slurred speech or problems with vision or balance. This medicine can also increase your risk of serious effects on the stomach or intestines including bleeding or perforation (forming of a hole). These conditions can be fatal and gastrointestinal effects can occur without warning at any time while you are taking anaprox. Older adults may have an even greater risk of these serious gastrointestinal side effects. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black bloody or tarry stools or coughing up blood or vomit that looks like coffee grounds. Do not use any other over-the-counter cold allergy or pain medication without first asking your doctor or pharmacist. Many medicines available over the counter contain aspirin or other medicines similar to anaprox (such as ibuprofen or ketoprofen). If you take certain products together you may accidentally take too much of this type of medication. Read the label of any other medicine you are using to see if it contains aspirin ibuprofen or ketoprofen. Do not drink alcohol while taking anaprox. Alcohol can increase the risk of stomach bleeding caused by anaprox. Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Naproxen can make your skin more sensitive to sunlight and sunburn may result. What should I discuss with my healthcare provider before taking anaprox? Taking an NSAID can increase your risk of life-threatening heart or circulation problems including heart attack or stroke. This risk will increase the longer you use an NSAID. Do not use this medicine just before or after having heart bypass surgery (also called coronary artery bypass graft or CABG). NSAIDs can also increase your risk of serious effects on the stomach or intestines including bleeding or perforation (forming of a hole). These conditions can be fatal and gastrointestinal effects can occur without warning at any time while you are taking an NSAID. Older adults may have an even greater risk of these serious gastrointestinal side effects. Do not use this medication if you are allergic to anaprox or if you have a history of allergic reaction to aspirin or other NSAIDs. Before taking anaprox tell your doctor if you are allergic to any drugs or if you have: • a history of heart attack stroke or blood clot; • heart disease congestive heart failure high blood pressure; • a history of stomach ulcers or bleeding; • liver or kidney disease; • asthma; • polyps in your nose; • a bleeding or blood clotting disorder; or • if you smoke. If you have any of these conditions you may not be able to use anaprox or you may need a dosage adjustment or special tests during treatment. FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Taking anaprox during the last 3 months of pregnancy may result in birth defects. Do not take anaprox during pregnancy unless your doctor has told you to. Naproxen can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medicine to a child younger than 2 years old without the advice of a doctor. How should I take anaprox? Take this medication exactly as directed on the label or as it has been prescribed by your doctor. Do not use the medication in larger amounts or use it for longer than recommended. EC-Naprosyn is a slower-acting form of anaprox and this brand should be used only for treating arthritis or ankylosing spondylitis. Follow your doctor's instructions. Do not crush chew or break an extended-release or enteric-coated tablet. Swallow the pill whole. The extended-release pill is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time. The enteric-coated pill has a special coating to protect your stomach. Breaking the pill could damage this coating. Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose measure the liquid with a marked measuring spoon or medicine cup not with a regular table spoon. If you do not have a dose-measuring device ask your pharmacist for one. If you take anaprox for a long period of time your doctor may want to check you on a regular basis to make sure this medication is not causing harmful effects. Do not miss any scheduled visits to your doctor. Store anaprox at room temperature away from moisture and heat. What happens if I miss a dose? Since anaprox is sometimes taken as needed you may not be on a dosing schedule. If you are taking the medication regularly take the missed dose as soon as you remember. If it is almost time for your next dose skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of a anaprox overdose may include nausea vomiting stomach pain confusion drowsiness black or bloody stools coughing up blood shallow breathing fainting or coma. What should I avoid while taking anaprox? Do not use any other over-the-counter cold allergy or pain medication without first asking your doctor or pharmacist. Many medicines available over the counter contain aspirin or other medicines similar to anaprox (such as ibuprofen or ketoprofen). If you take certain products together you may accidentally take too much of this type of medication. Read the label of any other medicine you are using to see if it contains aspirin ibuprofen or ketoprofen. Do not drink alcohol while taking anaprox. Alcohol can increase the risk of stomach bleeding caused by anaprox. Avoid prolonged exposure to sunlight. Naproxen may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable. Naproxen side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face lips tongue or throat. Stop taking anaprox and seek medical attention or call your doctor at once if you have any of these serious side effects: • chest pain weakness shortness of breath slurred speech problems with vision or balance; • black bloody or tarry stools; • coughing up blood or vomit that looks like coffee grounds; • swelling or rapid weight gain; • urinating less than usual or not at all; • nausea stomach pain low fever loss of appetite dark urine clay-colored stools jaundice (yellowing of the skin or eyes); • fever sore throat and headache with a severe blistering peeling and red skin rash; • bruising severe tingling numbness pain muscle weakness; or • fever headache neck stiffness chills increased sensitivity to light purple spots on the skin and/or seizure (convulsions). Keep taking anaprox and talk to your doctor if you have any of these less serious side effects: • upset stomach mild heartburn or stomach pain diarrhea constipation; • bloating gas; • dizziness headache nervousness; • skin itching or rash; • blurred vision; or • ringing in your ears. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect anaprox? Before taking anaprox tell your doctor if you are taking any of the following drugs: • a blood thinner such as warfarin (Coumadin); • lithium (Eskalith Lithobid); • methotrexate (Rheumatrex Trexall); • diuretics (water pills) such as furosemide (Lasix); • steroids (prednisone and others); • aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as diclofenac (Cataflam Voltaren) etodolac (Lodine) flurbiprofen (Ansaid) indomethacin (Indocin) ketoprofen (Orudis) ketorolac (Toradol) mefenamic acid (Ponstel) meloxicam (Mobic) nabumetone (Relafen) piroxicam (Feldene) and others; or • an ACE inhibitor such as benazepril (Lotensin) captopril (Capoten) fosinopril (Monopril) enalapril (Vasotec) lisinopril (Prinivil Zestril) ramipril (Altace) and others. If you are using any of these drugs you may not be able to use anaprox or you may need dosage adjustments or special tests during treatment. There may be other drugs not listed that can affect anaprox. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins minerals herbal products and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Generic Anaprox (Naproxen) Aleve Bonyl Diocodal Dysmenalgit Ec-naprosyn Equiproxen Floginax Laraflex Laser Mnpa Naixan Naprelan Napren Naprium Naprius Naprosine Naprosyn Naprux Naxen Naxyn Niaxan Nycopren Opipramol Panoxen Pranoxen Prexan Proxen Proxine Reuxen Veradol Xenar 250mg 100 pills 250mg 120 pills 250mg 60 pills 250mg 240 pills 250mg 80 pills Naproxen Anaprox