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Uprima (Apomorphine)

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Treating loss of control of body movements such as muscle stiffness slow movements or trouble moving associated with advanced Parkinson disease. Uprima (Apomorphine) is a dopamine agonist. It works by stimulating dopamine receptors which helps improve motor function. Also used to treat erectile dysfunction.

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About Uprima (Apomorphine):

Product Type: Other

Brand name: Uprima Generic name: Apomorphine Uprima (Apomorphine) is used for: Treating loss of control of body movements such as muscle stiffness slow movements or trouble moving associated with advanced Parkinson disease. Uprima (Apomorphine) is a dopamine agonist. It works by stimulating dopamine receptors which helps improve motor function. Do NOT use Uprima (Apomorphine) if: • you are allergic to any ingredient in Uprima (Apomorphine) (especially a sulfite) • you have decreased consciousness seizures or very low blood pressure • you are taking a 5-HT3 antagonist antiemetic (eg ondansetron dolasetron granisetron palonosetron alosetron) Contact your doctor or health care provider right away if any of these apply to you. Before using Uprima (Apomorphine): Some medical conditions may interact with Uprima (Apomorphine). Tell your doctor or pharmacist if you have any medical conditions especially if any of the following apply to you: • if you are pregnant planning to become pregnant or are breast-feeding • if you are taking any prescription or nonprescription medicine herbal preparation or dietary supplement • if you have allergies to medicines foods or other substances • if you have had a severe allergic reaction (eg severe rash hives difficulty breathing dizziness) to sulfites • if you have a history of low blood pressure dizziness fainting irregular or slow heartbeat or a history of a certain type of irregular heartbeat (eg congenital QT prolongation) low blood magnesium or potassium levels asthma liver problems kidney problems heart problems mental or mood problems sleep problems (eg falling asleep without warning) or stroke or other brain problems • if you regularly drink alcohol or if you have a history of alcohol or substance abuse Some MEDICINES MAY INTERACT with Uprima (Apomorphine). Tell your health care provider if you are taking any other medicines especially any of the following: • 5-HT3 antagonist antiemetics (eg ondansetron) because the risk of severe low blood pressure and loss of consciousness may be increased • Antiarrhythmics (eg amiodarone quinidine sotalol) arsenic azole antifungals (eg ketoconazole) bepridil cisapride droperidol H1 antagonists (eg astemizole terfenadine) ketolides (eg telithromycin) macrolide antibiotics (eg erythromycin) phenothiazines (eg thioridazine) phosphodiesterase type 5 inhibitors (eg vardenafil) pimozide quinolone antibiotics (eg ciprofloxacin) serotonin receptor antagonist antiemetics (eg dolasetron) tricyclic antidepressants (eg imipramine) or ziprasidone because the risk of serious side effects such as abnormal heart rhythms may be increased • Medicine for high blood pressure nitroglycerin or vasodilators (eg isosorbide) because they may increase the risk of Uprima (Apomorphine)'s side effects • Butyrophenones (eg haloperidol) metoclopramide phenothiazines (eg chlorpromazine) or thioxanthenes (eg thiothixene) because they may decrease Uprima (Apomorphine)'s effectiveness This may not be a complete list of all interactions that may occur. Ask your health care provider if Uprima (Apomorphine) may interact with other medicines that you take. Check with your health care provider before you start stop or change the dose of any medicine. How to use Uprima (Apomorphine): Use Uprima (Apomorphine) as directed by your doctor. Check the label on the medicine for exact dosing instructions. • An extra patient leaflet is available with Uprima (Apomorphine). Talk to your pharmacist if you have questions about this information. • Uprima (Apomorphine) is usually given as an injection at your doctor's office hospital or clinic. If you will be using Uprima (Apomorphine) at home a health care provider will teach you how to use it. Be sure you understand how to use Uprima (Apomorphine). Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions. • Uprima (Apomorphine) is for subcutaneous injection only. Do not inject Uprima (Apomorphine) into a vein. • Make sure you understand how to properly measure each dose of Uprima (Apomorphine) before injecting it. Ask your pharmacist for help if you are unsure of how to measure your dose. • Rotate sites where the medicine is injected. Do not always use the same site. • Do not inject medicine into a site that is sore red infected or damaged. • Do not use Uprima (Apomorphine) if it contains particles is cloudy or discolored or if the vial is cracked or damaged. • Your doctor may prescribe another medicine called an antiemetic before you start taking Uprima (Apomorphine) to lessen the nausea and vomiting that can occur when taking Uprima (Apomorphine). You may need to continue taking the antiemetic for the first 2 months of therapy. • Keep this product as well as syringes and needles out of the reach of children and pets. Do not reuse needles syringes or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal. • If you miss a dose of Uprima (Apomorphine) use it as soon as possible. If it is almost time for your next dose skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once. Ask your health care provider any questions you may have about how to use Uprima (Apomorphine). Important safety information: • Uprima (Apomorphine) may cause drowsiness dizziness or cause you to fall asleep without warning. These effects may be worse if you take it with alcohol or certain medicines. Use Uprima (Apomorphine) with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it. • Uprima (Apomorphine) may cause dizziness lightheadedness or fainting; alcohol hot weather exercise or fever may increase these effects. To prevent them sit up or stand slowly especially in the morning. Sit or lie down at the first sign of any of these effects. • Do not drink alcohol or use medicines that may cause drowsiness (eg sleep aids muscle relaxers) while you are using Uprima (Apomorphine); it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness. • Do NOT use more than the recommended dose of Uprima (Apomorphine) or use it more often than prescribed without checking with your doctor. • Some of these products contain sulfites. Sulfites may cause an allergic reaction in some patients (eg asthma patients). If you have ever had an allergic reaction to sulfites ask your pharmacist if your product has sulfites in it. • Patients with Parkinson disease may have an increased risk of developing a certain type of skin cancer (melanoma). It is not known if Uprima (Apomorphine) also increases the risk of melanoma. You may need to have skin exams while you are using Uprima (Apomorphine). Tell your doctor if you notice any unusual skin growths or a change in the appearance of a mole. Discuss any questions or concerns with your doctor. • Some people have experienced new unusual or increased urges (eg gambling sexual urges) while using Uprima (Apomorphine). Tell your doctor right away if you notice such effects. • Uprima (Apomorphine) may rarely cause a prolonged painful erection. This could happen even when you are not having sex. If this is not treated right away it could lead to permanent sexual problems such as impotence. Contact your doctor right away if this happens. • Do not suddenly stop taking Uprima (Apomorphine). Doing so may cause withdrawal symptoms like fever; stiff muscles; confusion; abnormal thinking; and fast or irregular heartbeat. Check with your doctor before you change your dose or stop Uprima (Apomorphine). • Lab tests including skin exams may be performed while you use Uprima (Apomorphine). These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. • Use Uprima (Apomorphine) with caution in the ELDERLY; they may be more sensitive to its effects especially confusion and hallucinations. • Uprima (Apomorphine) should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed. • PREGNANCY and BREAST-FEEDING: If you become pregnant contact your doctor. You will need to discuss the benefits and risks of using Uprima (Apomorphine) while you are pregnant. It is not known if Uprima (Apomorphine) is found in breast milk. Do not breast-feed while taking Uprima (Apomorphine). Some people who use Uprima (Apomorphine) for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction. Possible side effects of Uprima (Apomorphine): All medicines may cause side effects but many people have no or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome: • Bruising itching pain swelling or redness at the injection site; dizziness; drowsiness; flushing; headache; nausea; pale skin; runny nose; vomiting; yawning. Seek medical attention right away if any of these SEVERE side effects occur: • Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth face lips or tongue); agitation; chest pain; confusion; difficulty moving; fainting; falling asleep without warning; falling down; fast or irregular heartbeat; hallucinations; increased sweating; mental or mood changes (eg depression); new unusual or increased urges (eg gambling sexual urges); painful or prolonged erection; severe dizziness nausea or vomiting; severe or persistent headache; shortness of breath; sudden uncontrollable movements; swelling of the arms hands legs or feet; unusual change in the appearance of a mole or other skin growths; vision changes. This is not a complete list of all side effects that may occur. If you have questions about side effects contact your health care provider. Call your doctor for medical advice about side effects. If OVERDOSE is suspected: Symptoms may include agitation; chest pain; confusion; difficulty moving; grogginess; lightheadedness especially when standing; loss of consciousness; severe nausea or vomiting; slow heartbeat. Proper storage of Uprima (Apomorphine): Store Uprima (Apomorphine) at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat moisture and light. Do not store in the bathroom. Keep Uprima (Apomorphine) out of the reach of children and away from pets.

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Discount Prescription Drugs & Pain Medicine: Anaprox (Naproxen) Anaprox (Naproxen) is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and swelling (inflammation). It is also used to treat headaches muscle aches backaches etc. Buy Anaprox (Naproxen) and other Pain Medicine products online at Medstore. About Anaprox (Naproxen): Product Type: Pain Medicine Brand name: Anaprox Generic name: Naproxen What is anaprox? Naproxen is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Naproxen works by reducing hormones that cause inflammation and pain in the body. Naproxen is used to treat pain or inflammation caused by conditions such as arthritis ankylosing spondylitis tendinitis bursitis gout or menstrual cramps. Naproxen may also be used for purposes other than those listed in this medication guide. What is the most important information I should know about anaprox? This medicine can increase your risk of life-threatening heart or circulation problems including heart attack or stroke. This risk will increase the longer you use anaprox. Do not use this medicine just before or after having heart bypass surgery (also called coronary artery bypass graft or CABG). Seek emergency medical help if you have symptoms of heart or circulation problems such as chest pain weakness shortness of breath slurred speech or problems with vision or balance. This medicine can also increase your risk of serious effects on the stomach or intestines including bleeding or perforation (forming of a hole). These conditions can be fatal and gastrointestinal effects can occur without warning at any time while you are taking anaprox. Older adults may have an even greater risk of these serious gastrointestinal side effects. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black bloody or tarry stools or coughing up blood or vomit that looks like coffee grounds. Do not use any other over-the-counter cold allergy or pain medication without first asking your doctor or pharmacist. Many medicines available over the counter contain aspirin or other medicines similar to anaprox (such as ibuprofen or ketoprofen). If you take certain products together you may accidentally take too much of this type of medication. Read the label of any other medicine you are using to see if it contains aspirin ibuprofen or ketoprofen. Do not drink alcohol while taking anaprox. Alcohol can increase the risk of stomach bleeding caused by anaprox. Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Naproxen can make your skin more sensitive to sunlight and sunburn may result. What should I discuss with my healthcare provider before taking anaprox? Taking an NSAID can increase your risk of life-threatening heart or circulation problems including heart attack or stroke. This risk will increase the longer you use an NSAID. Do not use this medicine just before or after having heart bypass surgery (also called coronary artery bypass graft or CABG). NSAIDs can also increase your risk of serious effects on the stomach or intestines including bleeding or perforation (forming of a hole). These conditions can be fatal and gastrointestinal effects can occur without warning at any time while you are taking an NSAID. Older adults may have an even greater risk of these serious gastrointestinal side effects. Do not use this medication if you are allergic to anaprox or if you have a history of allergic reaction to aspirin or other NSAIDs. Before taking anaprox tell your doctor if you are allergic to any drugs or if you have: • a history of heart attack stroke or blood clot; • heart disease congestive heart failure high blood pressure; • a history of stomach ulcers or bleeding; • liver or kidney disease; • asthma; • polyps in your nose; • a bleeding or blood clotting disorder; or • if you smoke. If you have any of these conditions you may not be able to use anaprox or you may need a dosage adjustment or special tests during treatment. FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Taking anaprox during the last 3 months of pregnancy may result in birth defects. Do not take anaprox during pregnancy unless your doctor has told you to. Naproxen can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medicine to a child younger than 2 years old without the advice of a doctor. How should I take anaprox? Take this medication exactly as directed on the label or as it has been prescribed by your doctor. Do not use the medication in larger amounts or use it for longer than recommended. EC-Naprosyn is a slower-acting form of anaprox and this brand should be used only for treating arthritis or ankylosing spondylitis. Follow your doctor's instructions. Do not crush chew or break an extended-release or enteric-coated tablet. Swallow the pill whole. The extended-release pill is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time. The enteric-coated pill has a special coating to protect your stomach. Breaking the pill could damage this coating. Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose measure the liquid with a marked measuring spoon or medicine cup not with a regular table spoon. If you do not have a dose-measuring device ask your pharmacist for one. If you take anaprox for a long period of time your doctor may want to check you on a regular basis to make sure this medication is not causing harmful effects. Do not miss any scheduled visits to your doctor. Store anaprox at room temperature away from moisture and heat. What happens if I miss a dose? Since anaprox is sometimes taken as needed you may not be on a dosing schedule. If you are taking the medication regularly take the missed dose as soon as you remember. If it is almost time for your next dose skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of a anaprox overdose may include nausea vomiting stomach pain confusion drowsiness black or bloody stools coughing up blood shallow breathing fainting or coma. What should I avoid while taking anaprox? Do not use any other over-the-counter cold allergy or pain medication without first asking your doctor or pharmacist. Many medicines available over the counter contain aspirin or other medicines similar to anaprox (such as ibuprofen or ketoprofen). If you take certain products together you may accidentally take too much of this type of medication. Read the label of any other medicine you are using to see if it contains aspirin ibuprofen or ketoprofen. Do not drink alcohol while taking anaprox. Alcohol can increase the risk of stomach bleeding caused by anaprox. Avoid prolonged exposure to sunlight. Naproxen may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable. Naproxen side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face lips tongue or throat. Stop taking anaprox and seek medical attention or call your doctor at once if you have any of these serious side effects: • chest pain weakness shortness of breath slurred speech problems with vision or balance; • black bloody or tarry stools; • coughing up blood or vomit that looks like coffee grounds; • swelling or rapid weight gain; • urinating less than usual or not at all; • nausea stomach pain low fever loss of appetite dark urine clay-colored stools jaundice (yellowing of the skin or eyes); • fever sore throat and headache with a severe blistering peeling and red skin rash; • bruising severe tingling numbness pain muscle weakness; or • fever headache neck stiffness chills increased sensitivity to light purple spots on the skin and/or seizure (convulsions). Keep taking anaprox and talk to your doctor if you have any of these less serious side effects: • upset stomach mild heartburn or stomach pain diarrhea constipation; • bloating gas; • dizziness headache nervousness; • skin itching or rash; • blurred vision; or • ringing in your ears. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect anaprox? 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